Publications
My research integrates mechanobiology, evolutionary biology, functional
genomics, and epigenetics to understand musculoskeletal development,
skeletal morphology, and disease.
I have published 13 peer-reviewed articles, including 6 first-author papers, and currently have 1 first-author preprint, 1 manuscript under review, and 1 additional first-author manuscript in preparation.
Selected Peer-Reviewed Publications
1.
Okamoto AS, Coveney CR, Ganapathee DS, Capellini TD.
Massively parallel functional screen identifies thousands of regulatory
differences in human versus chimpanzee postcranial skeletal development.
Genome Biology and Evolution. 2026.
DOI
3.
Coveney CR*, Capellini TD.
Mechanoepigenetics in musculoskeletal disease.
Osteoarthritis and Cartilage. 2025.
DOI
4.
Coveney CR, Maridas D, Chen H, Muthuirulan P, Liu Z,
Jagoda E, Yarlagadda S, Movahhedi M, Proffen B, Rosen V, Kiapour AM,
Capellini TD.
Complex regulatory interactions at GDF5 shape joint morphology and
osteoarthritis disease risk. Arthritis & Rheumatology.
2025.
DOI
6.
Coveney CR, Samvelyan HJ, Miotla-Zarebska J, Carnegie J,
Chang E, Corrin CJ, Coveney T, Stott B, Parisi I, Duarte C, Vincent TL,
Staines KA, Wann AK.
Ciliary IFT88 protects coordinated adolescent growth plate ossification
from disruptive physiological mechanical forces.
Journal of Bone and Mineral Research. 2022.
DOI
7.
Coveney CR, Zhu L, Miotla-Zarebska J, Stott B, Parisi I,
Batchelor V, Duarte C, Chang E, McSorley E, Vincent TL, Wann AK.
The ciliary protein IFT88 controls post-natal cartilage thickness and
influences development of osteoarthritis.
Arthritis & Rheumatology. 2021.
DOI
10.
Coveney CR, Collins I, McFie M, Chanalaris A, Yamamoto K,
Wann AK.
Cilia protein IFT88 regulates extracellular protease activity by
optimizing LRP-1-mediated endocytosis.
FASEB Journal. 2018.
Preprints
1.
Coveney CR*, Maridas D, Kaushik D, Sarkar A, Ibata N,
McKeever A, Shoman J, Kistner T, Rubin G, Schell L, Venable E,
Allen-Bevins C, Ganapathee DS, Okamoto AS, Lieberman D, Carmody R,
Capellini TD.
Evolutionary trade-offs between growth and reproduction under obesogenic
conditions: Sex-biased skeletal and gonadal maturation in mice.
bioRxiv. 2026.
Preprint
Manuscripts Under Review
1.
Jung M, Alomar F, Coveney CR, Chen S, Orr S, Mimpen J,
Nikolic M, Flynn KA, Zhang Y, Ebsim R, Saunders FR, Gregory JS,
Aspden RM, Harvey NC, Lindner C, Abram SGF, Hammond C, Smith GD,
Zeggini E, Snelling S, Capellini TD, Rice S, Kemp JP, Tobias JH,
Cootes T, Faber BG.
Dissecting the genetic architecture of knee alignment reveals its
contribution to osteoarthritis risk.
Under review at Nature Communications.
Manuscripts in Preparation
1.
Coveney CR, Ganapathee DS, Sosa D, Okamoto AS,
Muthuirulan P, Amani MA, Jagoda E, Richard D, Jung M, Ebsim R,
Saunders F, Hashim A, Gregory J, Aspden R, Lindner C, Cootes T,
Kemp JP, Tobias JH, Faber BG, Capellini TD.
The functional legacy of Neandertal introgression across human tissues.
Manuscript in preparation.
* Corresponding author
